18 products were found matching "GeneID 5138"!

Active human PDE2A1 (GenBank Accession No. NM_002599), full length, with N-terminal GST tag, MW=132 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Human PDE2A (GenBank Accession No. NM_002599), amino-acids 2-941, with N-terminal FLAG tag, MW=106 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Assay conditions: 10 mM Tris-HCl, pH 7.4, 10 mM Mg

Protein function: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. [The UniProt Consortium]

Murine PDE2A, variant 1 (GenBank Accession No. NM_001143848), a.a 2-939 (end), with N-terminal GST tag, MW=132 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Murine PDE2A, variant 2 (GenBank Accession No. NM_001008548), a.a 2-935, with N-terminal GST tag, MW=132 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Murine PDE2A, variant 4 (GenBank Accession No. NM_001243757), a.a. 2-939 (end), with N-terminal GST tag, MW=132 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

The PDE2A Assay Kit is designed for identification of PDE2A inhibitors using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE2A to the binding agent. PDE2A plays an important role in dynamic regulation of cAMP signaling in the cardiovascular...

The PDE2A Assay Kit is designed for identification of PDE2A inhibitors using fluorescence polarization.The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE2A to the binding agent. PDE2A catalyzes the hydrolysis of the phosphodiester bond in dye-labeled cyclic adenosine...

The Mouse PDE2A Assay Kit is designed for identification of inhibitors of Mouse PDE2A using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by Mouse PDE2A to the binding agent. The key to the Mouse PDE2A Assay Kit is the specific binding agent. Using...

Phosphodiesterase 2A (PDE2A) is a cGMP-stimulated cyclic nucleotide phosphodiesterase that hydrolyzes cGMP and cAMP. It is a 941-amino acid protein comprised of an N-terminal domain (1-214), GAF-A domain (215-372), GAF-B domain (393-541), and a catalytic domain (579-941) and functions as a homodimer. PDE2A is...

Protein function: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line)...

alternative products:Additional isoforms seem to exist. Experimental confirmation may be lacking for some isoforms,catalytic activity:Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.,function:Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP).,similarity:Belongs to the cyclic nucleotide...